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These results altogether demonstrated the substantially enhanced ferroptosis-based antitumor efficacy of Gi-F-CAA for resolving large tumors in clinic, which might be attributed to the promoted drug delivery efficacy by deep tumor penetration, improved endocytosis, and AEB effect in cells

(There are excess secretions along the in the before picture, causing the vocal cord to appear focally white in the collision zone with the polyp.) Before After A pedunculated left (right side of image) vocal cord hemorrhagic polyp before and after (2 months) microlaryngeal surgical excision.

Follow-up outcome data were not available for one female patient who was transferred to a different hospital shortly after scanning

Graphical abstract Similar content being viewed by others Background Nephropathic cystinosis is a rare, autosomal recessive lysosomal storage disease with an incidence of 1:100,000 to 1:200,000 live births [1]

(3) RAPTORmembrane engagement and intermediate enzyme activation